Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050871 | 0.92 | DRD2 (0.67) | DRD2SIGMAR1OPRM1OPRK1DRD3 | |
| SCHEMBL9052433 | 0.86 | DRD2 (0.68) | DRD2DRD3ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11553970 | 0.85 | DRD2 (0.67) | DRD2SIGMAR1HTR7 | |
| SCHEMBL9052603 | 0.79 | DRD2 (0.71) | DRD2SIGMAR1OPRM1OPRK1DRD3 | |
| SCHEMBL8986029 | 0.78 | DRD2 (1.00) | DRD2SIGMAR1OPRM1OPRK1DRD3 | |
| SCHEMBL27739798 | 0.78 | MEN1 (0.56) | DRD2SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9052577 | 0.78 | DRD2 (0.63) | DRD2DRD3ADRA1AADRA1DADRA1B | |
| SCHEMBL7689578 | 0.77 | OPRL1 (0.63) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL27830596 | 0.77 | KMT2A (0.55) | DRD2SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9052143 | 0.77 | OPRM1 (0.48) | NPC1CASP3RAB9ASENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |