Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365784 | 0.81 | ALDH1A1 (0.31) | ALDH1A1TDP1CYP11B1CYP11B2 | |
| SCHEMBL8368241 | 0.81 | ALDH1A1 (0.31) | ALDH1A1TDP1CYP11B1CYP11B2 | |
| SCHEMBL8539803 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TDP1GPBAR1MAPK1CYP11B1 | |
| SCHEMBL8537689 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TDP1GPBAR1MAPK1CYP11B1 | |
| SCHEMBL8365821 | 0.79 | LTC4S (0.35) | ALDH1A1TDP1GPBAR1CYP11B1CYP11B2 | |
| SCHEMBL8365636 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TDP1GPBAR1CYP11B1CYP11B2 | |
| SCHEMBL9052220 | 0.76 | — | — | |
| SCHEMBL11891094 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL7507021 | 0.71 | GPBAR1 (0.33) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 | |
| SCHEMBL27804377 | 0.71 | CYP11B1 (0.40) | ALDH1A1TDP1GPBAR1MAPK1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038141-A1 | 2-(1H-4(5)-IMIDAZOYL) CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 1996-12-05 | — | — | WO | disclosed |