Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053658 | 0.83 | PKM (0.41) | CYP3A4ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL247055 | 0.82 | ALDH1A1 (0.32) | CYP3A4ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL2363793 | 0.80 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TSHRTP53 | |
| SCHEMBL8029715 | 0.80 | ALDH1A1 (0.31) | CYP3A4ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL10437871 | 0.80 | ALDH1A1 (0.31) | CYP3A4ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL9746230 | 0.76 | TSHR (0.49) | TSHRMAPT | |
| SCHEMBL28947782 | 0.76 | TSHR (0.43) | CYP3A4TDP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6422138 | 0.76 | — | — | |
| SCHEMBL28977828 | 0.75 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1362421 | 0.75 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041824-A1 | GRAFT COPOLYMERS AND THEIR PRODUCTION | IMPERIAL EXPLOITATION LIMITED (GB) | 1996-12-27 | — | — | WO | disclosed |
| US-5382633-A | Modified polymers | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1995-01-17 | — | — | US | disclosed |
| EP-0431015-A1 | MODIFIED POLYMERS | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0357267-A1 | Modified polymers | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-03-07 | — | — | EP | disclosed |
| WO-1990001506-A1 | MODIFIED POLYMERS | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1990-02-22 | — | — | WO | disclosed |