Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323568 | 0.90 | ALDH1A1 (0.37) | PKMKDM4EMEN1KMT2ACYP4F2 | |
| SCHEMBL9052373 | 0.83 | CYP3A4 (0.35) | ALDH1A1MAPK1HIF1ATP53CYP3A4 | |
| SCHEMBL2348598 | 0.82 | ALDH1A1 (0.38) | PKMKDM4EMEN1KMT2ACYP4F2 | |
| SCHEMBL247055 | 0.80 | ALDH1A1 (0.32) | ALDH1A1MAPK1HIF1ATP53CYP3A4 | |
| SCHEMBL10437871 | 0.79 | ALDH1A1 (0.31) | ALDH1A1MAPK1HIF1ATP53CYP3A4 | |
| SCHEMBL8029715 | 0.79 | ALDH1A1 (0.31) | ALDH1A1MAPK1HIF1ATP53CYP3A4 | |
| SCHEMBL29073969 | 0.78 | PKM (0.47) | PKMKDM4EMEN1KMT2ACYP4F2 | |
| SCHEMBL2710202 | 0.77 | PKM (0.40) | PKMKDM4EMEN1KMT2ACYP4F2 | |
| SCHEMBL5819364 | 0.76 | ALDH1A1 (0.39) | PKMKDM4EMEN1KMT2ACYP4F2 | |
| SCHEMBL1361264 | 0.76 | CYP4F2 (0.44) | PKMKDM4EMEN1KMT2ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541115-B1 | COSMETIC | JGC CATALYSTS & CHEMICALS LTD (JP) | 2011-06-01 | — | — | EP | disclosed |
| EP-1541115-A1 | COSMETIC | Catalysts & Chemicals Industries Co., Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20050118220-A1 | Cosmetics | CATALYSTS& CHEMICALS INDUSTRIES CO., LTD (JP) | 2005-06-02 | — | — | US | disclosed |