SCHEMBL9052394

SCHEMBL9052394

O=C(O)c1cc(O)c(OCc2ccccc2)c(O)c1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.74
HPGD P15428 1/20 0.74
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
NR4A2 P43354 2/20 0.57
NR4A1 P22736 1/20 0.57
NR4A3 Q92570 1/20 0.57
SRD5A2 P31213 2/20 0.54
PLA2G4B P0C869 1/20 0.50
PTPN1 P18031 1/20 0.50
GLRA1 P23415 1/20 0.49
MCL1 Q07820 1/20 0.49
MAOB P27338 1/20 0.49
P2RY14 Q15391 1/20 0.48
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PTGER1 P34995 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17971071 0.87 LMNA (0.75) LMNAHPGDMEN1KMT2ANR4A2
SCHEMBL29136466 0.87 HPGD (0.66) LMNAHPGDMEN1KMT2ASMN1; SMN2
SCHEMBL22015355 0.85 LMNA (0.78) LMNAHPGDKMT2ASMN1; SMN2
SCHEMBL16250484 0.85 LMNA (1.00) LMNAHPGDMEN1KMT2APTPN1
SCHEMBL2227072 0.85 LMNA (0.56) LMNAHPGDMEN1KMT2ANR4A2
SCHEMBL10597121 0.83 LMNA (0.65) LMNAHPGDMEN1KMT2APTPN1
SCHEMBL30307916 0.83 MEN1 (0.61) LMNAHPGDMEN1KMT2ANR4A2
SCHEMBL4876543 0.83 MEN1 (0.61) LMNAHPGDMEN1KMT2ANR4A2
SCHEMBL793724 0.83 MEN1 (0.65) LMNAHPGDMEN1KMT2ANR4A2
SCHEMBL4308031 0.83 MEN1 (0.65) LMNAHPGDMEN1KMT2ANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed