Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307916 | 1.00 | MEN1 (0.61) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL2227072 | 0.94 | LMNA (0.56) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL30307871 | 0.92 | POLB (0.66) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL7045904 | 0.86 | MEN1 (0.56) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL30102539 | 0.85 | LMNA (0.76) | MEN1KMT2AHPGDLMNANPC1 | |
| SCHEMBL4874871 | 0.85 | LMNA (0.76) | MEN1KMT2AHPGDLMNANPC1 | |
| SCHEMBL3960943 | 0.84 | NR4A2 (0.58) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL3965806 | 0.84 | EGFR (0.64) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL27527174 | 0.84 | MEN1 (0.54) | MEN1KMT2AMRGPRX4NR4A2NR4A1 | |
| SCHEMBL9052394 | 0.83 | LMNA (0.74) | MEN1KMT2ANR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-03-20 | — | — | US | disclosed |
| US-7288273-B1 | Gallotannins and ellagitannins as regulators of cytokine release | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-10-30 | — | — | US | disclosed |
| EP-1232169-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036436-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-25 | — | — | WO | disclosed |
| EP-0491600-A1 | Process for the regiospecific monofunctionalisation of a phenolic hydroxy group of a polyphenol | ROUSSEL UCLAF (FR) | 1992-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | IL2, IL6, TNF | MEN1 2640/4885KMT2A 3946/4885MRGPRX4 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.