Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983425 | 0.91 | HPGD (0.84) | LMNAHPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL30892445 | 0.91 | HPGD (0.84) | LMNAHPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL1458077 | 0.90 | LMNA (0.82) | LMNAHPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL18397048 | 0.90 | HPGD (0.82) | LMNAHPGDTSHRALDH1A1KDM4E | |
| SCHEMBL22136381 | 0.90 | LMNA (0.82) | LMNAHPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL22015355 | 0.88 | LMNA (0.78) | LMNAHPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL21738207 | 0.87 | HPGD (0.77) | LMNAHPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL4874871 | 0.87 | LMNA (0.76) | LMNAHPGDXDHKDM4EPOLB | |
| SCHEMBL30102539 | 0.87 | LMNA (0.76) | LMNAHPGDXDHKDM4EPOLB | |
| SCHEMBL2338199 | 0.86 | HPGD (0.76) | LMNAHPGDTSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119233964-A | Single component delivery system for nucleic acids | 宾夕法尼亚大学理事会 | 2024-12-31 | — | — | CN | disclosed |
| US-20240252677-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2024-08-01 | — | — | US | disclosed |
| EP-4347550-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | The Trustees of the University of Pennsylvania (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2023198812-A1 | COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | SUPERBRANCHE (FR) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198813-A1 | DENDRITIC MOLECULES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | SUPERBRANCHE (FR) | 2023-10-19 | — | — | WO | disclosed |
| EP-4261244-A1 | DENDRITIC MOLECULES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | Superbranche (FR) | 2023-10-18 | — | — | EP | disclosed |
| EP-4260876-A1 | COMPOSITIONS OF DISPERSED SYSTEMS FOR BIOMEDICAL APPLICATIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | Superbranche (FR) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022251191-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-12-01 | — | — | WO | disclosed |
| CN-109970765-B | Antitumor compound | 中国科学院化学研究所 | 2020-08-11 | — | — | CN | disclosed |
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
| US-9403944-B2 | Antipathogenic guanidinium copolymer | LOMBARDI JOHN L (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150011716-A1 | Antipathogenic Guanidinium Copolymer | LOMBARDI JOHN L (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2014184503-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2014-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | MSR1, CD74, CD4 | LMNA 2564/4885HPGD 3144/4885TSHR 1795/4885 |
| US-20240252677-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | TLR3, TLR9, ADAR | LMNA 2652/4885HPGD 4615/4885TSHR 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.