Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873642 | 0.84 | ACHE (0.58) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL11579347 | 0.79 | ACHE (0.52) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL29746015 | 0.77 | ALDH1A1 (0.72) | ACHELMNAALDH1A1GAAKMT2A | |
| SCHEMBL29391895 | 0.77 | ACHE (0.68) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL456868 | 0.77 | ALDH1A1 (0.72) | ACHELMNAALDH1A1GAAKMT2A | |
| SCHEMBL29398372 | 0.77 | ALDH1A1 (0.72) | ACHELMNAALDH1A1GAAKMT2A | |
| SCHEMBL492314 | 0.77 | ACHE (0.68) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL7993466 | 0.77 | NPSR1 (0.52) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL12228133 | 0.76 | ACHE (0.67) | ACHELMNAALDH1A1GAADRD2 | |
| SCHEMBL29369744 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040170-A2 | METAL-CONTAINING COMPOUNDS AND THEIR USE FOR INHIBITING THE IMMUNE RESPONSE | PROCEPT, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040170-A2 | METAL-CONTAINING COMPOUNDS AND THEIR USE FOR INHIBITING THE IMMUNE RESPONSE | PROCEPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |