Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.49 |
| ▸ | HTR1B | P28222 | 4/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305578 | 0.82 | MAPK14 (0.57) | HTR1AHTR1DHTR1BALDH1A1DRD2 | |
| SCHEMBL9053159 | 0.75 | WDR5 (0.48) | HTR1AHTR1DHTR1BHTR6ALDH1A1 | |
| SCHEMBL6305476 | 0.73 | HTR1A (0.54) | HTR1AHTR1DHTR1BKCNH2HTR6 | |
| SCHEMBL6313054 | 0.73 | MAPT (0.61) | HTR1AHTR1DHTR1BKCNH2HTR6 | |
| SCHEMBL6308893 | 0.73 | HTR1A (0.50) | HTR1AHTR1DHTR1BKCNH2CYP1A2 | |
| SCHEMBL6393026 | 0.72 | HTR1A (0.52) | HTR1AHTR1DHTR1BCYP1A2ALDH1A1 | |
| SCHEMBL6308250 | 0.72 | HTR1A (0.49) | HTR1AHTR1DHTR1BCDK2 | |
| SCHEMBL8115641 | 0.72 | MAPK14 (0.49) | HTR1AHTR1DHTR1BTNIKKCNH2 | |
| SCHEMBL6308472 | 0.71 | HTR1A (0.54) | HTR1AHTR1DHTR1BHTR6HRH4 | |
| SCHEMBL6313298 | 0.71 | HTR1A (0.63) | HTR1AHTR1DHTR1BCYP1A2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |