Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305447 | 0.84 | WDR5 (0.52) | WDR5HTR1AHTR1DHTR1BALDH1A1 | |
| SCHEMBL6313939 | 0.84 | WDR5 (0.54) | WDR5ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL6305795 | 0.83 | KMT2A (0.58) | WDR5HTR1AHTR1DHTR1BBRD4 | |
| SCHEMBL6307926 | 0.83 | SIRT6 (0.52) | WDR5HTR1AHTR1DHTR1BALDH1A1 | |
| SCHEMBL6308059 | 0.79 | GABRP (0.48) | HTR1AHTR1DHTR1BBRD4PIM1 | |
| SCHEMBL6313812 | 0.79 | WDR5 (0.60) | WDR5ALDH1A1POLBKMT2AGAA | |
| SCHEMBL9052843 | 0.75 | HTR1A (0.49) | HTR1AHTR1DHTR1BALDH1A1KMT2A | |
| SCHEMBL6305476 | 0.74 | HTR1A (0.54) | HTR1AHTR1DHTR1BHTR6CDK2 | |
| SCHEMBL9058689 | 0.72 | HTR1A (0.64) | WDR5HTR1AHTR1DHTR1B | |
| SCHEMBL6313054 | 0.71 | MAPT (0.61) | HTR1AHTR1DHTR1BPOLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |