Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418501 | 0.89 | CES1 (0.45) | CDC25ACNR2CNR1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL6308299 | 0.88 | CES1 (0.44) | CDC25ACNR2CNR1ALDH1A1ALDH2 | |
| SCHEMBL10578138 | 0.82 | OPRM1 (0.48) | CDC25AALDH1A1HPGD | |
| SCHEMBL254004 | 0.81 | CDC25A (0.70) | CDC25ACNR2CNR1ALDH1A1ALDH2 | |
| SCHEMBL8592697 | 0.80 | CDC25A (0.49) | CDC25ACNR2CNR1ALDH1A1CYP3A4 | |
| SCHEMBL8134283 | 0.78 | CNR2 (0.36) | CDC25ACNR2CNR1ALDH1A1ALDH2 | |
| SCHEMBL1521088 | 0.77 | AADAT (0.49) | CDC25ACNR2CNR1ALDH1A1ALDH2 | |
| SCHEMBL4415292 | 0.73 | ALDH1A1 (0.44) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL31653849 | 0.72 | ALDH1A1 (0.42) | CDC25ACNR2CNR1ALDH1A1CYP3A4 | |
| SCHEMBL19380275 | 0.72 | ALDH1A1 (0.42) | CDC25ACNR2CNR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703901-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | Astra Aktiebolag (SE) | 1996-04-03 | — | — | EP | claimed |
| WO-1994029272-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | claimed |
| JP-2104778-A | — | — | None | — | — | JP | disclosed |
| CN-110437230-A | A kind of three-level aminated compounds and biphosphine ligand, wherein mesosome and preparation method | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-11-12 | — | — | CN | disclosed |
| US-4921503-A | FOR HAIR, INDOLINE DYES, NO OXIDIZER REQUIRED | CLAIROL INCORPORATED (US) | 1990-05-01 | — | — | US | disclosed |
| JP-H02104778-A | NEW DYING COMPOSITION AND DYING | BRISTOL MYERS SQUIBB CO | 1990-04-17 | — | — | JP | disclosed |