Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RGS12 | O14924 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465913 | 0.83 | MAPT (0.56) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7466381 | 0.81 | MEN1 (0.58) | KDM4EKMT2AMEN1RAB9AMAPT | |
| SCHEMBL28056488 | 0.81 | KDM4E (0.57) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL9052435 | 0.80 | MEN1 (0.60) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7465966 | 0.79 | KDM4E (0.59) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7461237 | 0.78 | MAPT (0.50) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7466251 | 0.78 | KDM4E (0.56) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL8830493 | 0.78 | KDM4E (0.56) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7466256 | 0.78 | KDM4E (0.56) | KDM4EKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7459907 | 0.76 | EGFR (0.57) | KDM4EKMT2AMEN1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700388-A1 | SUBSTITUTED BETA-ARYL AND BETA-HETEROARYL-ALPHA-CYANOACRYLAMIDE DERIVATIVES AS TYROSINE KINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-03-13 | — | — | EP | claimed |
| WO-1995026341-A1 | SUBSTITUTED BETA-ARYL AND BETA-HETEROARYL-ALPHA-CYANOACRYLAMIDE DERIVATIVES AS TYROSINE KINASE INHIBITORS | PHARMACIA S.P.A. (IT) | 1995-10-05 | — | — | WO | claimed |