Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.43 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22921868 | 0.85 | TSHR (0.58) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 | |
| SCHEMBL13222535 | 0.82 | SMN1; SMN2 (0.56) | EPHX2TSHR | |
| SCHEMBL9054540 | 0.82 | EPHX2 (0.53) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 | |
| SCHEMBL2289168 | 0.80 | CYP4F2 (0.56) | CYP4A11CYP4F2L3MBTL1NPC1RAB9A | |
| SCHEMBL6535275 | 0.79 | EPHX2 (0.57) | EPHX2TSHRL3MBTL1 | |
| SCHEMBL12508639 | 0.78 | TSHR (0.50) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 | |
| SCHEMBL1863579 | 0.78 | CALM1 (0.55) | EPHX2CYP4A11CYP4F2TSHR | |
| SCHEMBL1928824 | 0.78 | PLAAT3 (0.51) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 | |
| SCHEMBL1866015 | 0.78 | CYP4A11 (0.50) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 | |
| SCHEMBL3456495 | 0.78 | CYP4A11 (0.53) | EPHX2CYP4Z1CYP4F11CYP4F12CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| WO-1996004246-A1 | PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |