SCHEMBL3456495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22921868	0.92	TSHR (0.58)	CYP4A11CYP4F2TSHREPHX2ALOX5
	SCHEMBL3409184	0.89	CYP4A11 (0.68)	CYP4A11CYP4F2TSHREPHX2ALOX5
	SCHEMBL1410420	0.89	CYP4A11 (0.56)	CYP4A11CYP4F2TSHREPHX2ALDH1A1
	SCHEMBL1928824	0.85	PLAAT3 (0.51)	CYP4A11CYP4F2TSHREPHX2ALOX5
	SCHEMBL1863579	0.85	CALM1 (0.55)	CYP4A11CYP4F2TSHREPHX2ALDH1A1
	SCHEMBL13061462	0.85	TSHR (0.50)	CYP4A11CYP4F2TSHREPHX2ALDH1A1
	SCHEMBL26239913	0.85	ALDH1A1 (0.55)	CYP4A11CYP4F2TSHREPHX2ALDH1A1
	SCHEMBL12508639	0.85	TSHR (0.50)	CYP4A11CYP4F2TSHREPHX2ALOX5
	SCHEMBL1866015	0.85	CYP4A11 (0.50)	CYP4A11CYP4F2TSHREPHX2ALOX5
	SCHEMBL10583619	0.85	TSHR (0.50)	CYP4A11CYP4F2TSHREPHX2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.