Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.72 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.68 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808132 | 0.91 | ALOX5 (0.63) | ALOX5CYSLTR1 | |
| SCHEMBL8800199 | 0.87 | ALOX5 (0.72) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9053241 | 0.87 | CYSLTR1 (0.73) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10696181 | 0.86 | ALOX5 (0.69) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10692276 | 0.84 | ALOX5 (1.00) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL1419799 | 0.84 | ALOX5 (0.64) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| Acetic Acid Methyl Ester SCHEMBL27424540 | 0.83 | CYSLTR1 (0.66) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9827537 | 0.82 | CYSLTR1 (0.83) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9053620 | 0.82 | CYSLTR1 (0.59) | ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9431922 | 0.82 | MEN1 (0.53) | ALOX5CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004246-A1 | PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |
| US-5420131-A | Platelet activating factor antagonist or 5-lipoxygenase inhibitors | J. URIACH & CIA, S.A. (ES) | 1995-05-30 | — | — | US | disclosed |
| EP-0617032-A1 | Cyanomethylpyridine derivatives as PAF antagonists and 5-lipoxygenase inhibitors | J. URIACH & CIA. S.A. (ES) | 1994-09-28 | — | — | EP | disclosed |
| US-4769461-A | Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |