Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053877 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8977326 | 0.72 | MAPT (0.38) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9047337 | 0.72 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9050188 | 0.72 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8514392 | 0.68 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL2408324 | 0.68 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8795939 | 0.68 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8795450 | 0.68 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9158238 | 0.62 | SPHK1 (0.59) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9158242 | 0.62 | SPHK1 (0.59) | ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | claimed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | claimed |
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | disclosed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | disclosed |