Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053453 | 0.80 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9050784 | 0.70 | KDM1A (0.38) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9158242 | 0.64 | SPHK1 (0.59) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9158238 | 0.64 | SPHK1 (0.59) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL23993582 | 0.63 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8794667 | 0.62 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL12165287 | 0.62 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL9158687 | 0.62 | SPHK1 (0.54) | — | |
| SCHEMBL9158680 | 0.62 | SPHK1 (0.54) | — | |
| SCHEMBL9156554 | 0.62 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | claimed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | claimed |
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | disclosed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | disclosed |