Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199411 | 0.72 | TACR1 (0.48) | TACR1 | |
| SCHEMBL4135034 | 0.72 | TACR1 (0.48) | TACR1 | |
| SCHEMBL5551503 | 0.71 | ALDH1A1 (0.70) | — | |
| SCHEMBL8530555 | 0.71 | TACR1 (0.46) | TACR1 | |
| SCHEMBL8176205 | 0.71 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6424614 | 0.71 | TACR1 (0.47) | TACR1 | |
| SCHEMBL310305 | 0.71 | TACR1 (0.44) | TACR1 | |
| Hydrochloric Acid SCHEMBL8537523 | 0.70 | TACR1 (0.87) | TACR1 | |
| SCHEMBL8701287 | 0.69 | NOTUM (0.42) | TACR1 | |
| SCHEMBL5198211 | 0.68 | TACR1 (0.43) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394150-B1 | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2011-01-19 | — | — | EP | disclosed |