Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705898 | 0.76 | NOTUM (0.48) | NOTUMMAPTALDH1A1HSP90AA1HPGD | |
| SCHEMBL7517331 | 0.74 | TACR1 (0.54) | TACR1 | |
| SCHEMBL8327571 | 0.74 | NOTUM (0.48) | NOTUMMAPTALDH1A1HSP90AA1HPGD | |
| SCHEMBL1973007 | 0.72 | ALDH1A1 (0.61) | MAPTALDH1A1HSP90AA1HPGDHTT | |
| SCHEMBL5551503 | 0.71 | ALDH1A1 (0.70) | NOTUMMAPTALDH1A1HSP90AA1HPGD | |
| SCHEMBL8326571 | 0.70 | LMNA (0.50) | MAPTALDH1A1HSP90AA1HPGDHTT | |
| SCHEMBL8328197 | 0.70 | MAPT (0.50) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8327843 | 0.69 | NOS1 (0.41) | MAPTALDH1A1HSP90AA1HPGDHTT | |
| SCHEMBL905349 | 0.69 | TACR1 (0.49) | TACR1 | |
| SCHEMBL12513443 | 0.68 | TSHR (0.48) | MAPTALDH1A1HSP90AA1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |