Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5304269 | 0.95 | CYP1A2 (0.78) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Fumaric Acid SCHEMBL8865851 | 0.94 | CYP1A2 (0.69) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Maleic Acid SCHEMBL8865839 | 0.94 | CYP1A2 (0.69) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Maleic Acid SCHEMBL8866481 | 0.89 | CYP1A2 (0.69) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Fumaric Acid SCHEMBL8866493 | 0.89 | CYP1A2 (0.69) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Remacemide SCHEMBL20769836 | 0.88 | CYP1A2 (1.00) | CYP1A2CYP3A4RECQLMAPK1ALDH1A1 | |
| Remacemide SCHEMBL151148 | 0.88 | CYP1A2 (1.00) | CYP1A2CYP3A4RECQLMAPK1ALDH1A1 | |
| SCHEMBL5306970 | 0.86 | CYP1A2 (0.72) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| SCHEMBL8866735 | 0.86 | CYP3A4 (0.72) | CYP1A2CYP3A4RECQLMAPK1RAB9A | |
| Remacemide SCHEMBL635940 | 0.86 | MAPK1 (1.00) | CYP1A2CYP3A4RECQLMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |