Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312789 | 0.83 | RORC (0.48) | BTKALDH1A1HPGDMEN1GAA | |
| SCHEMBL21369339 | 0.81 | DRD2 (0.55) | LSSDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL6306797 | 0.80 | IKBKB (0.36) | LSSDRD2KCNH2DRD3IKBKB | |
| SCHEMBL6305712 | 0.79 | DRD2 (0.43) | LSSDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL6305391 | 0.77 | GABRP (0.52) | ALDH1A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL6313627 | 0.76 | RORC (0.49) | MEN1RAB9AKMT2A | |
| SCHEMBL13698245 | 0.72 | DRD2 (0.61) | DRD2HTR2AHTR2CSLC6A4 | |
| SCHEMBL6307413 | 0.71 | HTR1D (0.48) | DRD2SLC6A4 | |
| SCHEMBL27937830 | 0.69 | SLC6A4 (0.38) | DRD2SLC6A4GAAMAPT | |
| SCHEMBL20861913 | 0.68 | IKBKB (0.53) | DRD2HTR2AHTR2CKCNH2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |