Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955611 | 0.77 | LTB4R (0.64) | MAOBMEN1KMT2ANR4A2NR4A1 | |
| SCHEMBL8070497 | 0.77 | MAOB (0.61) | MAOBMEN1KMT2ANR4A2NR4A1 | |
| SCHEMBL10891366 | 0.77 | MAOB (0.56) | MAOBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL20234843 | 0.76 | MAOB (0.74) | MAOBMAPTL3MBTL1LTB4RLTB4R2 | |
| SCHEMBL20394187 | 0.75 | ALOX5 (0.54) | MAOBMEN1KMT2AALOX5L3MBTL1 | |
| SCHEMBL6035603 | 0.75 | MAOB (0.64) | MAOBNR4A2NR4A1NR4A3ALOX5 | |
| SCHEMBL15935622 | 0.74 | LIPE (0.51) | MAOBMEN1KMT2ANR4A2NR4A1 | |
| SCHEMBL24159702 | 0.74 | MAOB (0.54) | MAOBMEN1KMT2ANR4A2ALOX5 | |
| SCHEMBL2133357 | 0.74 | MAOB (0.54) | MAOBALOX5L3MBTL1LMNA | |
| SCHEMBL8937667 | 0.74 | MEN1 (0.61) | MAOBMEN1KMT2ANR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |