Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408743 | 0.85 | ALDH1A1 (0.47) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL12354522 | 0.82 | ALDH1A1 (0.50) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15475791 | 0.80 | KDM4E (0.47) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15475487 | 0.80 | KDM4E (0.47) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15171934 | 0.78 | KDM4E (0.48) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL23870903 | 0.77 | MEN1 (0.50) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL12422456 | 0.77 | KDM4E (0.48) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL12422449 | 0.77 | KDM4E (0.48) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4921067 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL12422450 | 0.77 | KDM4E (0.48) | RAB9AKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002524-A1 | PHENYLCARBAMATE DERIVATIVES SUITABLE TO THE USE AS ANTICHOLINESTERASE SUBSTANCES | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1996-02-01 | — | — | WO | disclosed |