Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9053642

N[C@@H]1C[C@@H]1F.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OAT P04181 1/20 0.42
GABRR1 P24046 1/20 0.42
SLC6A12 P48065 3/20 0.37
SLC6A11 P48066 3/20 0.37
SLC6A13 Q9NSD5 3/20 0.37
ABAT P80404 2/20 0.33
SLC1A2 P43004 2/20 0.32
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM1A O60341 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
KDM5C P41229 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
KDM3A Q9Y4C1 1/20 0.31
DPP4 P27487 2/20 0.31
DPP8 Q6V1X1 2/20 0.31
DPP9 Q86TI2 2/20 0.31
DPP7 Q9UHL4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL10365398 1.00 OAT (0.42) OATGABRR1SLC6A12SLC6A11SLC6A13
Trifluoroacetic Acid SCHEMBL3025153 0.78 OAT (0.36) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL30278992 0.77 THRB (0.50) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL9122104 0.77 THRB (0.50) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL28133460 0.76 OAT (0.35) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL3154232 0.76 OAT (0.35) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL3708706 0.74 OAT (0.34) OATGABRR1DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL31447631 0.73 CHRM3 (0.36) OATGABRR1SLC1A2
Trifluoroacetic Acid SCHEMBL7211625 0.73 CHRM3 (0.36) OATGABRR1SLC1A2
Trifluoroacetic Acid SCHEMBL507990 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996001262-A1 NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF HANMI PHARMACEUTICAL CO., LTD. (KR) 1996-01-18 WO disclosed
EP-0191185-B1 QUINOLINE-CARBOXYLIC ACID DERIVATIVES DAIICHI SEIYAKU CO., LTD. (JP) 1990-03-07 EP disclosed
US-4871852-A BACTERICIDES AGAINST GRAMNEGATIVE AND GRAMPOSITIVE DAIICHI SEIYAKU CO., LTD. (JP) 1989-10-03 US disclosed
EP-0191185-A1 Quinoline-carboxylic acid derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1986-08-20 EP disclosed