Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OAT | P04181 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9122104 | 1.00 | THRB (0.50) | THRBMEN1KMT2AOATMMP2 | |
| Trifluoroacetic Acid SCHEMBL3043598 | 0.85 | MMP8 (0.33) | OATMMP2MMP1MMP8DPP4 | |
| Cyclohexylamine SCHEMBL1787821 | 0.83 | ALDH1A1 (0.36) | MMP2MMP1MMP8CHRM3 | |
| Cycloheptanamine SCHEMBL27746259 | 0.83 | ALDH1A1 (0.36) | MMP2MMP1MMP8CHRM3 | |
| Trifluoroacetic Acid SCHEMBL3708706 | 0.82 | OAT (0.34) | OATGABRR1DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3025153 | 0.81 | OAT (0.36) | THRBOATGABRR1DPP4DPP8 | |
| Bicarbonate SCHEMBL10933373 | 0.81 | THRB (0.67) | THRBMEN1KMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL17062500 | 0.81 | GABRR1 (0.43) | MEN1KMT2AOATGABRR1 | |
| Trifluoroacetic Acid SCHEMBL17078325 | 0.80 | THRB (0.31) | THRBMEN1KMT2AOAT | |
| Trifluoroacetic Acid SCHEMBL18603585 | 0.80 | THRB (0.31) | THRBMEN1KMT2AOAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384493-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |