Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140061 | 0.84 | HTR2C (0.40) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL1583458 | 0.83 | OPRM1 (0.39) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL2530710 | 0.75 | RXFP1 (0.43) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL6474586 | 0.73 | OPRM1 (0.46) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL7400751 | 0.72 | SCN9A (0.43) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL5667100 | 0.72 | ALDH1A1 (0.49) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL7093301 | 0.71 | HTR2C (0.40) | HTR1AADRA1AADRA1BNOTUM | |
| SCHEMBL10817746 | 0.70 | KMT2A (0.48) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2530053 | 0.68 | GRM2 (0.45) | OPRM1OPRL1GRM2HTR1AADRA1A | |
| SCHEMBL233169 | 0.67 | ADRB1 (0.58) | HTR1AKDM4EDRD2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |