Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | DNM2 | P50570 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054449 | 0.75 | CHRNA7 (0.42) | TAAR1HRH3CHRNA7HRH4 | |
| SCHEMBL12539197 | 0.72 | KDM4E (0.44) | NOS3NOS1NOS2GAA | |
| SCHEMBL7748837 | 0.71 | NOS3 (0.48) | TAAR1HRH3CHRNA7NOS3NOS1 | |
| SCHEMBL31644385 | 0.71 | TAAR1 (0.49) | TAAR1HRH3CHRNA7 | |
| SCHEMBL9332019 | 0.68 | HTR1A (0.39) | TAAR1HRH3HTR2AHTR2CHTR2B | |
| SCHEMBL30086100 | 0.67 | KDM4E (0.58) | TAAR1HRH3 | |
| SCHEMBL229256 | 0.67 | KDM4E (0.58) | TAAR1HRH3 | |
| SCHEMBL11445213 | 0.67 | CYP2D6 (0.51) | TAAR1HRH3CHRNA7NOS3NOS1 | |
| SCHEMBL7535532 | 0.67 | HRH3 (0.34) | TAAR1HRH3HTR2AHTR2CHTR2B | |
| SCHEMBL2495475 | 0.67 | KCNH2 (0.48) | DNM2NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000248-A1 | WATER MISCIBLE NON-HYDROLYZABLE CROSS-LINKERS AND HIGH REFRACTIVE INDEX HYDROGELS PREPARED THEREWITH | KABI PHARMACIA OPHTHALMICS, INC. (US) | 1996-01-04 | — | — | WO | claimed |
| WO-1996000248-A1 | WATER MISCIBLE NON-HYDROLYZABLE CROSS-LINKERS AND HIGH REFRACTIVE INDEX HYDROGELS PREPARED THEREWITH | KABI PHARMACIA OPHTHALMICS, INC. (US) | 1996-01-04 | — | — | WO | disclosed |
| US-5439950-A | Intraocular lenses | KABI PHARMACIA OPHTHALMICS, INC. (US) | 1995-08-08 | — | — | US | disclosed |