Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054827 | 0.87 | CNR2 (0.58) | CRHBPCRHR2ALDH1A1HTTNCOA1 | |
| SCHEMBL9054159 | 0.87 | ALDH1A1 (0.55) | CRHBPCRHR2ALDH1A1HTTNCOA1 | |
| SCHEMBL29339298 | 0.84 | L3MBTL1 (0.51) | MTNR1AMTNR1BALDH1A1GPR139 | |
| SCHEMBL16889096 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL6813188 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| Hydrochloric Acid SCHEMBL6813768 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL10669545 | 0.81 | ALDH1A1 (0.69) | MTNR1AMTNR1BCRHBPCRHR2ALDH1A1 | |
| SCHEMBL3281313 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BCRHBPCRHR2GPR139 | |
| SCHEMBL18793985 | 0.80 | MEN1 (0.65) | ALDH1A1SMN1; SMN2GPR139POLB | |
| SCHEMBL8866666 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |