Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 3/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386113 | 0.91 | DHFR (0.51) | DCPSDHFRSLC2A1 | |
| SCHEMBL8388586 | 0.78 | CDK9 (0.45) | HSP90AA1DCPSDHFRSLC2A1 | |
| SCHEMBL8389944 | 0.75 | SLC2A1 (0.44) | DCPSDHFRSLC2A1 | |
| SCHEMBL1155078 | 0.74 | DCPS (0.66) | DCPSDHFR | |
| SCHEMBL8389945 | 0.74 | DCPS (0.47) | DCPSDHFRSLC2A1 | |
| SCHEMBL27776400 | 0.73 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1 | |
| SCHEMBL18305717 | 0.71 | DCPS (0.47) | HSP90AA1HSP90AB1DCPSDHFR | |
| SCHEMBL1154716 | 0.70 | DHFR (0.63) | DCPSDHFR | |
| SCHEMBL30268652 | 0.69 | TYMS (0.55) | HSP90AB1DCPSDHFRSLC2A1 | |
| SCHEMBL14353311 | 0.69 | DCPS (0.63) | DCPSDHFRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684824-A4 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES. | FMC CORP (US) | 1996-02-14 | — | — | EP | claimed |
| EP-0684824-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1995-12-06 | — | — | EP | claimed |