Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466865 | 0.81 | KDM1A (0.43) | KDM1ACYP3A4MEN1CYP2D6ALOX15 | |
| SCHEMBL3455254 | 0.81 | CYP3A4 (0.42) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| SCHEMBL6838308 | 0.78 | CYP3A4 (0.40) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| SCHEMBL9053824 | 0.78 | KDM1A (0.41) | KDM1ACYP3A4MEN1CYP2D6ALOX15 | |
| SCHEMBL414650 | 0.76 | CYP3A4 (0.44) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| Benzene SCHEMBL28485309 | 0.75 | SIGMAR1 (0.44) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL28152573 | 0.75 | CYP3A4 (0.43) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| SCHEMBL28893830 | 0.74 | CYP3A4 (0.37) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| SCHEMBL10595033 | 0.73 | CYP3A4 (0.42) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 | |
| SCHEMBL6985972 | 0.73 | CYP3A4 (0.42) | CYP3A4MEN1CYP2D6ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498755-A | IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS | ALLERGAN, INC. | 1996-03-12 | — | — | US | disclosed |
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |