Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053636 | 0.92 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2 | |
| SCHEMBL9053968 | 0.86 | ALOX5 (0.64) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL8648449 | 0.85 | FFAR1 (0.76) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL9054244 | 0.82 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL28298920 | 0.79 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL9057072 | 0.79 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL8712492 | 0.78 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL7801457 | 0.78 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2 | |
| SCHEMBL22209124 | 0.78 | FFAR1 (0.80) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 | |
| SCHEMBL8800199 | 0.78 | ALOX5 (0.72) | CYSLTR1CYSLTR2FFAR1AKR1B1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004246-A1 | PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |