Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578273 | 0.77 | PNMT (0.42) | HTTALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL9050295 | 0.77 | HTT (0.46) | SIRT6HTTALDH1A1LMNAGAA | |
| SCHEMBL9055266 | 0.76 | SIRT6 (0.44) | SIRT6HTTALDH1A1LMNAGAA | |
| SCHEMBL23363844 | 0.76 | ALDH1A1 (0.39) | HTTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL3626555 | 0.72 | SIRT6 (0.49) | SIRT6HTTALDH1A1LMNAGAA | |
| SCHEMBL427403 | 0.69 | SIRT6 (0.59) | SIRT6HTTALDH1A1LMNAGAA | |
| SCHEMBL2016171 | 0.69 | SIRT6 (0.69) | SIRT6ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL21275246 | 0.69 | SIRT6 (0.69) | SIRT6ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL7803729 | 0.68 | HTT (0.60) | SIRT6HTTALDH1A1LMNAGAA | |
| SCHEMBL9300572 | 0.68 | ALDH1A1 (0.58) | SIRT6HTTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724580-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011243-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |