Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515752 | 0.77 | LMNA (0.59) | KDM4ECES2CES1AKR1B1SMN1; SMN2 | |
| SCHEMBL24825774 | 0.76 | TDP1 (0.53) | KDM4ERAB9AMAPTL3MBTL1POLB | |
| SCHEMBL19476144 | 0.76 | MMP13 (0.60) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL24356066 | 0.73 | KMT2A (0.58) | KDM4ESMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL18040177 | 0.72 | NAPRT (0.53) | KDM4ESMN1; SMN2HPGDPOLBALDH1A1 | |
| SCHEMBL2668039 | 0.72 | — | — | |
| SCHEMBL10977792 | 0.72 | — | — | |
| SCHEMBL8617913 | 0.72 | — | — | |
| SCHEMBL165337 | 0.71 | — | — | |
| SCHEMBL6287457 | 0.70 | KDM4E (0.69) | KDM4ESMN1; SMN2HPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002538-A1 | FUNGICIDAL 2-IMIDAZOLINE-5-ONE DERIVATIVES | RHONE POULENC AGROCHIMIE (FR) | 1996-02-01 | — | — | WO | disclosed |