Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520162 | 0.89 | TSHR (0.40) | TSHRKLK7TDP1KMT2ABRD4 | |
| SCHEMBL698490 | 0.84 | — | — | |
| SCHEMBL24629297 | 0.82 | KMT2A (0.42) | KLK7KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2597869 | 0.82 | ALDH1A1 (0.43) | KLK7TDP1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14167163 | 0.82 | TSHR (0.52) | TSHRKLK7TDP1KMT2AMEN1 | |
| SCHEMBL337416 | 0.81 | BRD4 (0.50) | TSHRTDP1KMT2ABRD4ALDH1A1 | |
| SCHEMBL697221 | 0.80 | ALDH1A1 (0.50) | TSHRKLK7TDP1KMT2AMEN1 | |
| SCHEMBL697966 | 0.80 | TSHR (0.50) | TSHRKLK7TDP1KMT2AMEN1 | |
| SCHEMBL2907816 | 0.79 | HPGD (0.53) | TSHRKLK7TDP1KMT2AMEN1 | |
| SCHEMBL9130829 | 0.79 | HPGD (0.53) | TSHRKLK7TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101918363-A | Phenyl acetamide derivative | ASTELLAS PHARMA INC | 2010-12-15 | — | — | CN | disclosed |
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |