Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057805 | 0.91 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9054244 | 0.90 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL29587847 | 0.85 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9057183 | 0.84 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9719811 | 0.83 | GPBAR1 (0.62) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9053620 | 0.81 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ALOX5 | |
| Ammonia Solution, Strong SCHEMBL9585183 | 0.81 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9057089 | 0.79 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL7008427 | 0.79 | GPBAR1 (0.64) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL8800199 | 0.78 | ALOX5 (0.72) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004246-A1 | PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |