Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 8/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054630 | 0.83 | DRD2 (0.44) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL9050996 | 0.80 | HTR1A (0.44) | DRD2DRD3HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL6017101 | 0.79 | HTR1A (0.43) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL9051452 | 0.79 | KDM4E (0.46) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL2056185 | 0.76 | DRD2 (0.57) | DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL8549470 | 0.76 | MAPT (0.46) | HTR1AHTR1DHTR1BMAPK1KDM4E | |
| SCHEMBL13169913 | 0.73 | HRH4 (0.52) | HRH4MAPK1HTR2CHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3680678 | 0.72 | HRH4 (0.51) | HRH4MAPK1HTR2CHTTALDH1A1 | |
| SCHEMBL6313298 | 0.70 | HTR1A (0.63) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL6002177 | 0.69 | HTR1A (0.62) | DRD2DRD3HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | claimed |
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |