Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 13/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054339 | 0.87 | HPRT1 (0.78) | HPRT1POLBTYMPPOLA1POLG | |
| SCHEMBL10871616 | 0.76 | TK1 (0.46) | HPRT1PNP | |
| SCHEMBL64568 | 0.75 | HPRT1 (1.00) | HPRT1POLBTYMPPOLA1POLG | |
| Phosphoric Acid SCHEMBL3497655 | 0.74 | HPRT1 (0.98) | HPRT1POLBTYMPPOLA1POLG | |
| SCHEMBL9054351 | 0.71 | HPRT1 (0.87) | HPRT1PNP | |
| SCHEMBL9417162 | 0.70 | HPRT1 (0.72) | HPRT1POLBPNP | |
| SCHEMBL9053851 | 0.70 | HPRT1 (0.85) | HPRT1PNP | |
| SCHEMBL9857606 | 0.69 | HPRT1 (0.69) | HPRT1PNP | |
| SCHEMBL9054652 | 0.68 | HPRT1 (0.55) | HPRT1POLBTYMPPOLA1POLG | |
| Gs-438 SCHEMBL64567 | 0.68 | POLB (0.80) | HPRT1POLBPOLA1POLGPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | claimed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | claimed |