SCHEMBL9055017

SCHEMBL9055017

CC(C)c1cc(C(C)C)c(S(=O)(=O)Oc2cc(C(=O)O)cc(O)c2O)c(C(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.47
FABP3 P05413 2/20 0.44
FABP4 P15090 2/20 0.44
FABP5 Q01469 1/20 0.44
ENPP3 O14638 2/20 0.44
ENPP1 P22413 2/20 0.44
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41
ANTXR2 P58335 1/20 0.41
THRA P10827 3/20 0.40
THRB P10828 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA3 P07451 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9053200 0.76 PTGS2 (0.51) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9052519 0.75 PTGS2 (0.50) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9061556 0.71 PTGS2 (0.49) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9055319 0.71 MAPT (0.47) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL5265908 0.71 PTGS2 (0.59) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9054334 0.71 PTGS2 (0.51) PTGS2ENPP3ENPP1POLBPOLA1
SCHEMBL15524731 0.70 CA1 (0.61) PTGS2FABP3FABP4GABRA1GABRB2
SCHEMBL9052978 0.70 PTGS2 (0.47) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL7937565 0.70 PTGS2 (0.51) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9059958 0.70 TPMT (0.47) PTGS2POLBPOLA1ANTXR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed