Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110875 | 0.92 | EBP (0.58) | LTA4HHRH3KCNH2EBPSIGMAR1 | |
| SCHEMBL3861283 | 0.89 | EBP (0.58) | LTA4HHRH3KCNH2EBPSIGMAR1 | |
| SCHEMBL7529231 | 0.88 | EBP (0.57) | LTA4HHRH3KCNH2EBPSIGMAR1 | |
| SCHEMBL7110262 | 0.87 | LTA4H (0.57) | LTA4HHRH3EBPSIGMAR1MCHR1 | |
| SCHEMBL7109616 | 0.85 | EBP (0.56) | LTA4HHRH3EBPSIGMAR1PSMB1 | |
| SCHEMBL7110375 | 0.84 | EBP (0.56) | LTA4HHRH3EBPSIGMAR1MCHR1 | |
| SCHEMBL7111804 | 0.84 | EBP (0.54) | LTA4HHRH3KCNH2EBPSIGMAR1 | |
| SCHEMBL8605470 | 0.83 | EBP (0.49) | LTA4HHRH3KCNH2EBPSIGMAR1 | |
| SCHEMBL3975634 | 0.81 | EBP (0.72) | LTA4HHRH3EBPSIGMAR1ESR1 | |
| SCHEMBL7521111 | 0.80 | EBP (0.70) | LTA4HHRH3EBPSIGMAR1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009051-A1 | A METHOD FOR MINIMIZING THE UTEROTROPHIC EFFECT OF TAMOXIFEN AND TAMOXIFEN ANALOGS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |