Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | FES | P07332 | 1/20 | 0.31 |
| ▸ | FER | P16591 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056288 | 0.87 | ALDH1A1 (0.41) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL9056121 | 0.84 | CES1 (0.39) | GRIA1GRIA2GRIA3GRIA4FLT3 | |
| SCHEMBL9056705 | 0.84 | SMN1; SMN2 (0.34) | CA1CA2CA4CA7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8327819 | 0.83 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8327814 | 0.83 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL2050673 | 0.83 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4FLT3 | |
| SCHEMBL2947383 | 0.83 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4FLT3 | |
| SCHEMBL9472971 | 0.83 | POLB (0.40) | CA1CA2CA4CA7FYN | |
| SCHEMBL9472968 | 0.83 | POLB (0.40) | CA1CA2CA4CA7FYN | |
| Hydrochloric Acid SCHEMBL3142414 | 0.82 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522494-B1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1996-10-02 | — | — | EP | claimed |
| US-5223527-A | Isatineoxime derivatives and their use | NEUROSEARCH A/S (DK) | 1993-06-29 | — | — | US | claimed |
| EP-0522494-A1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-01-13 | — | — | EP | claimed |
| EP-0522494-B1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1996-10-02 | — | — | EP | disclosed |
| US-5223527-A | Isatineoxime derivatives and their use | NEUROSEARCH A/S (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0522494-A1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-01-13 | — | — | EP | disclosed |