Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | FES | P07332 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056485 | 0.85 | TSHR (0.38) | CES1ALDH1A1ALDH2ALDH3A1CYP3A4 | |
| SCHEMBL9055355 | 0.84 | GRIA1 (0.31) | ALDH1A1FLT3PDPK1ROCK2FES | |
| SCHEMBL9207029 | 0.81 | CES1 (0.40) | CES1ALDH1A1ALDH2ALDH3A1SRC | |
| SCHEMBL9055477 | 0.81 | CES1 (0.41) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL9055513 | 0.78 | CASP3 (0.47) | CES1ALDH1A1DNMT1CYP3A4SMN1; SMN2 | |
| SCHEMBL9057244 | 0.77 | CASP3 (0.48) | ALDH1A1CYP3A4SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL23412593 | 0.72 | ALDH1A1 (0.49) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL9056288 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19LMNA | |
| SCHEMBL23412305 | 0.69 | ALDH1A1 (0.49) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL8133363 | 0.68 | PDPK1 (0.40) | ALDH1A1FLT3PDPK1ROCK2FES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522494-B1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1996-10-02 | — | — | EP | disclosed |
| US-5223527-A | Isatineoxime derivatives and their use | NEUROSEARCH A/S (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0522494-A1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-01-13 | — | — | EP | disclosed |