Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 6/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 6/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9188896 | 0.98 | SLC18A3 (0.43) | SLC18A3LMNATSHRCYP3A4TDP1 | |
| SCHEMBL17703862 | 0.89 | SLC18A3 (0.49) | SLC18A3LMNATSHRCYP3A4TDP1 | |
| Acetic Acid SCHEMBL9056408 | 0.81 | LMNA (0.44) | LMNATSHRCYP3A4TDP1BLM | |
| Acetic Acid SCHEMBL2455498 | 0.77 | TSHR (0.44) | LMNATSHRCYP3A4TDP1BLM | |
| Acetic Acid SCHEMBL9188687 | 0.75 | CYP3A4 (0.33) | LMNATSHRCYP3A4TDP1BLM | |
| Acetic Acid SCHEMBL15820199 | 0.74 | BBOX1 (0.42) | LMNATSHRCYP3A4TDP1BLM | |
| Acetic Acid SCHEMBL30330546 | 0.73 | BBOX1 (0.47) | LMNATSHRCYP3A4TDP1BLM | |
| SCHEMBL10256421 | 0.72 | APOBEC3A (0.46) | SLC18A3LMNATSHRCYP3A4TDP1 | |
| Acetic Acid SCHEMBL30330339 | 0.71 | BBOX1 (0.48) | LMNATSHRCYP3A4TDP1BLM | |
| Acetic Acid SCHEMBL25212436 | 0.70 | BBOX1 (0.53) | LMNATSHRCYP3A4TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314619-B1 | Epoxy resin mixture | CIBA GEIGY AG (CH) | 1996-07-10 | — | — | EP | disclosed |
| US-4885354-A | Epoxy resin compositions | CIBA-GEIGY CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0314619-A2 | Epoxy resin mixture | CIBA-GEIGY AG (CH) | 1989-05-03 | — | — | EP | disclosed |