Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL927376 | 0.98 | BBOX1 (0.55) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL30329879 | 0.94 | LMNA (0.54) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29251899 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29252285 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29251720 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29251803 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL15208533 | 0.93 | BBOX1 (0.50) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29251829 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL29252554 | 0.93 | LMNA (0.57) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR | |
| Acetic Acid SCHEMBL30330953 | 0.92 | LMNA (0.56) | BBOX1LMNAAPOBEC3AAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | BASF SE (DE) | 2026-05-05 | — | — | US | claimed |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BASF SE (DE) | 2025-12-30 | — | — | US | claimed |
| US-20230348657-A1 | SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT | BASF SE (DE) | 2023-11-02 | — | — | US | claimed |
| US-20230323013-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2023-10-12 | — | — | US | claimed |
| EP-4185627-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2023-05-31 | — | — | EP | claimed |
| EP-4185626-A1 | SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT | BASF SE (DE) | 2023-05-31 | — | — | EP | claimed |
| CN-116134063-A | Application of ring opening of uretdione at low temperature and normal pressure | 巴斯夫欧洲公司 | 2023-05-16 | — | — | CN | claimed |
| WO-2022018213-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2022-01-27 | — | — | WO | claimed |
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | BASF SE (DE) | 2026-05-05 | — | — | US | disclosed |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BASF SE (DE) | 2025-12-30 | — | — | US | disclosed |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BASF SE (DE) | 2025-12-30 | — | — | US | disclosed |
| US-20230348657-A1 | SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348657-A1 | SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230323013-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4185627-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2023-05-31 | — | — | EP | disclosed |
| EP-4185626-A1 | SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT | BASF SE (DE) | 2023-05-31 | — | — | EP | disclosed |
| CN-116137864-A | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | 巴斯夫欧洲公司 | 2023-05-19 | — | — | CN | disclosed |
| CN-116134063-A | Application of ring opening of uretdione at low temperature and normal pressure | 巴斯夫欧洲公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| WO-2022018213-A1 | APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE | BASF SE (DE) | 2022-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | UQCRB, SCO2, UTS2R | BBOX1 1545/4885LMNA 108/4885APOBEC3A 2434/4885 |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BMP1, BMP4, PBRM1 | BBOX1 830/4885LMNA 163/4885APOBEC3A 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.