Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770820 | 0.75 | POLB (0.63) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL30285929 | 0.75 | POLB (0.63) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL8990319 | 0.75 | POLB (0.63) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL19343021 | 0.73 | POLB (0.61) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL29462500 | 0.73 | ALDH1A1 (0.56) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL4386835 | 0.73 | ALDH1A1 (0.56) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL3397538 | 0.73 | NPC1 (0.58) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL1165271 | 0.71 | POLB (0.53) | MAPK1NPC1ALDH1A1POLBHSD17B10 | |
| SCHEMBL9643856 | 0.71 | HTR1A (0.74) | ALDH1A1POLBHSD17B10TSHRCYP1A2 | |
| SCHEMBL11826902 | 0.71 | POLB (0.63) | MAPK1NPC1ALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013553-A1 | DISARO COLORANT | ZENECA LIMITED (GB) | 1996-05-09 | — | — | WO | disclosed |