Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 15/20 | 0.74 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417148 | 0.87 | HPRT1 (0.57) | HPRT1TYMPMEN1ALDH1A1LMNA | |
| SCHEMBL84258 | 0.85 | HPRT1 (1.00) | HPRT1FGFR1SLC22A6TYMPMEN1 | |
| SCHEMBL9055682 | 0.83 | HPRT1 (0.81) | HPRT1FGFR1SLC22A6TYMPMEN1 | |
| SCHEMBL9858182 | 0.82 | HPRT1 (0.62) | HPRT1 | |
| SCHEMBL9576807 | 0.81 | HPRT1 (0.67) | HPRT1 | |
| SCHEMBL9684438 | 0.81 | HPRT1 (0.54) | HPRT1 | |
| Ammonia Solution, Strong SCHEMBL9126239 | 0.80 | HPRT1 (0.65) | HPRT1 | |
| SCHEMBL9685371 | 0.80 | HPRT1 (0.54) | HPRT1 | |
| SCHEMBL9417162 | 0.80 | HPRT1 (0.72) | HPRT1 | |
| SCHEMBL9675861 | 0.80 | HPRT1 (0.53) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | claimed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | claimed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | claimed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | claimed |
| JP-3017090-A | — | — | None | — | — | JP | disclosed |
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | disclosed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| JP-H0317090-A | NOVEL COMPOUND, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH COMPOUND | BEECHAM GROUP PLC | 1991-01-25 | — | — | JP | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | disclosed |