Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043902 | 0.89 | SCN9A (0.44) | MMP3 | |
| SCHEMBL9040580 | 0.88 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9058733 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9061279 | 0.85 | MMP3 (0.42) | MMP3AGTR1AGTR2GPR119 | |
| SCHEMBL9057823 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9056117 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9055944 | 0.79 | MMP3 (0.43) | MMP3AGTR1AGTR2GPR119 | |
| SCHEMBL9057258 | 0.77 | MMP3 (0.40) | MMP3GPR119 | |
| SCHEMBL9040583 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9055893 | 0.77 | MMP3 (0.43) | MMP3AGTR1AGTR2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |