Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043899 | 0.89 | SCN9A (0.41) | MMP3AGTR1AGTR2 | |
| SCHEMBL9040574 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9058732 | 0.88 | AGTR2 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9061264 | 0.85 | MMP3 (0.40) | MMP3AGTR1AGTR2GPR119ALOX5AP | |
| SCHEMBL9057816 | 0.85 | AGTR2 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9057254 | 0.79 | MMP3 (0.38) | MMP3AGTR1AGTR2GPR119ALOX5AP | |
| SCHEMBL9056026 | 0.79 | MMP3 (0.39) | MMP3AGTR1AGTR2GPR119ALOX5AP | |
| SCHEMBL9062806 | 0.79 | MMP3 (0.39) | MMP3AGTR1AGTR2GPR119ALOX5AP | |
| SCHEMBL9059392 | 0.79 | GPR119 (0.39) | MMP3AGTR1AGTR2GPR119ALOX5AP | |
| SCHEMBL9055940 | 0.79 | MMP3 (0.42) | MMP3GPR119ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |