Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452391 | 0.82 | CYP3A4 (0.36) | MEN1KMT2APOLBALDH1A1TSHR | |
| SCHEMBL17906986 | 0.77 | PRKDC (0.42) | MEN1KMT2APKMPOLBALDH1A1 | |
| SCHEMBL27749294 | 0.77 | BCHE (0.37) | PKMALDH1A1TSHR | |
| SCHEMBL27846360 | 0.75 | HRH4 (0.31) | — | |
| SCHEMBL1191487 | 0.73 | MEN1 (0.40) | MEN1KMT2APOLBALDH1A1TSHR | |
| SCHEMBL20258198 | 0.70 | HTR2A (0.41) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL18011076 | 0.69 | ADRB1 (0.58) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL27989607 | 0.69 | PLD1 (0.51) | SIGMAR1PLD1ALDH1A1HSD17B10 | |
| SCHEMBL31465185 | 0.68 | SIGMAR1 (0.49) | SIGMAR1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3566412 | 0.68 | HTR2C (0.42) | SIGMAR1ADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045551-A | Compound as thyroid hormone beta receptor agonist and application thereof | 广东东阳光药业有限公司 | 2021-06-29 | — | — | CN | claimed |
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |
| CN-103842332-B | Cyclopropylamine compound | 武田药品工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| WO-1996003378-A1 | N-PHENYLATED AMIDE AND UREA DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |