Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749294 | 0.82 | BCHE (0.37) | TSHRRAB9AALDH1A1 | |
| SCHEMBL17906986 | 0.82 | PRKDC (0.42) | TSHRMAPTPOLBMEN1NPC1 | |
| SCHEMBL9055973 | 0.82 | SIGMAR1 (0.39) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1191487 | 0.78 | MEN1 (0.40) | TSHRMAPTPOLBNPSR1MAPK1 | |
| SCHEMBL15397914 | 0.72 | ALDH1A1 (0.34) | CYP3A4CYP2C9TSHRCYP2C19MAPT | |
| SCHEMBL28099160 | 0.72 | POLB (0.44) | TSHRMAPTPOLBNPSR1MAPK1 | |
| SCHEMBL6601213 | 0.71 | MAPT (0.40) | CYP3A4CYP2C9TSHRCYP2C19MAPT | |
| SCHEMBL28086933 | 0.70 | CHEK1 (0.33) | POLBNPSR1ALOX15MAP2K1ADORA3 | |
| SCHEMBL27846360 | 0.69 | HRH4 (0.31) | — | |
| SCHEMBL7627710 | 0.67 | POLB (0.35) | POLBNPSR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |