Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745272 | 0.86 | SLC22A12 (0.60) | CYP3A4ALOX15HPGDARCYP2C19 | |
| SCHEMBL15864338 | 0.79 | ALOX5 (0.70) | HPGDALOX5KDM4ETSHRMEN1 | |
| SCHEMBL5138931 | 0.78 | KDM4E (0.74) | CYP3A4ALOX15HPGDCYP1A2CYP2C19 | |
| SCHEMBL15865400 | 0.72 | AR (0.47) | CYP3A4ALOX15HPGDARCYP1A2 | |
| SCHEMBL7332022 | 0.71 | CYP3A4 (0.62) | CYP3A4ALOX15HPGDARCYP1A2 | |
| SCHEMBL5433434 | 0.71 | KDM4E (0.74) | CYP3A4ALOX15HPGDARCYP2C19 | |
| SCHEMBL1874869 | 0.70 | HPGD (0.79) | CYP3A4ALOX15HPGDARCYP1A2 | |
| SCHEMBL15864329 | 0.70 | KDM4E (0.64) | CYP3A4ALOX15HPGDCYP2C19LMNA | |
| SCHEMBL17270585 | 0.70 | KDM4E (0.57) | HPGDLMNAADORA3ALOX5KDM4E | |
| SCHEMBL6426148 | 0.69 | TUBB4A (0.63) | CYP3A4ALOX15ADORA3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012489-A1 | BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |